N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID
D-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-
CAS: 34404-28-9
Molecular Formula: C10H17NO6
N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID - Names and Identifiers
N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID - Physico-chemical Properties
| Molecular Formula | C10H17NO6 |
| Molar Mass | 247.25 |
| Density | 1.264 |
| Melting Point | 108 °C(dec.) |
| Boling Point | 435.9±35.0 °C(Predicted) |
| Specific Rotation(α) | 14 ° (C=1, MeOH) |
| Flash Point | 217.4 °C |
| Water Solubility | Soluble in water |
| Appearance | Crystalline powder |
| Color | White to Almost white |
| pKa | 3.83±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 14 ° (C=1, MeOH) |
| MDL | MFCD00190790 |
N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29225090 |
N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID - Introduction
D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-is an organic compound with the chemical structure of C11H19NO6. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to white solid
-Melting point: approx. 125-128°C
-Solubility: Soluble in common solvents
-Chemical properties: It is a stable compound that is not easy to react under common conditions.
Use:
- D-Glutamic acid is an amino acid and is one of the components of proteins in organisms. The protecting group of the N-tert-butoxycarbonyl group can serve to protect the glutamic acid functional group during synthesis and is used in organic synthesis.
-It can also be used in the field of peptide synthesis and protein chemical synthesis, as a synthetic intermediate with special functions.
Preparation Method:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-usually synthesized by N-protecting glutamic acid molecules. The specific preparation method can be used to synthesize the intermediate of tert-butyl dimethyl azide by chlorooxide, and then deprotect under the condition of acid catalysis formed by silicate to obtain D-Glutamic acid, N-[(1,1-dimethoxy) carbonyl]-.
Safety Information:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-is considered to be low toxic under normal conditions, but it still needs to follow laboratory safety procedures.
-Avoid direct exposure to sensitive areas such as skin, eyes and mucous membranes during handling and use.
-Avoid contact with oxidants and strong acids during storage and handling.
-In case of accidental ingestion or exposure, seek immediate medical assistance.
Nature:
-Appearance: Colorless to white solid
-Melting point: approx. 125-128°C
-Solubility: Soluble in common solvents
-Chemical properties: It is a stable compound that is not easy to react under common conditions.
Use:
- D-Glutamic acid is an amino acid and is one of the components of proteins in organisms. The protecting group of the N-tert-butoxycarbonyl group can serve to protect the glutamic acid functional group during synthesis and is used in organic synthesis.
-It can also be used in the field of peptide synthesis and protein chemical synthesis, as a synthetic intermediate with special functions.
Preparation Method:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-usually synthesized by N-protecting glutamic acid molecules. The specific preparation method can be used to synthesize the intermediate of tert-butyl dimethyl azide by chlorooxide, and then deprotect under the condition of acid catalysis formed by silicate to obtain D-Glutamic acid, N-[(1,1-dimethoxy) carbonyl]-.
Safety Information:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-is considered to be low toxic under normal conditions, but it still needs to follow laboratory safety procedures.
-Avoid direct exposure to sensitive areas such as skin, eyes and mucous membranes during handling and use.
-Avoid contact with oxidants and strong acids during storage and handling.
-In case of accidental ingestion or exposure, seek immediate medical assistance.
Last Update：2024-04-09 15:17:56
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Product Name: BOC-D-Glutamic acid Visit Supplier Webpage Request for quotationCAS: 34404-28-9
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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